Clinical Pearl

Remember that kidney failure in the hepatitis C cirrhotic patient might be related to the virus itself! Cryoglobulinemia, membranous glomerulonephritis, MPGN and polyarteritis nodosa are all associated with HCV, and therefore you might entertain a serologic workup that includes a cryocrit, C3-C4 levels, ESR and P-ANCA.

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