Pathology: prurigo nodularis

prurigo nodularis

Prurigo nodularis can be seen in liver disease.  Pruritus develops after the deposition of bile acids in the skin.  Repetitive scratching can, in some patients, lead to the development of hyperpigmented nodules.  This finding does not require skin biopsy.  The treatment of PN should cater to the underlying disease, ie. relieve the cholestasis.

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