Definition: ABO-incompatible liver transplant

The ABO-incompatible liver transplant is an important way to expand the donor pool, and most studies show survival outcomes on par with those from the blood type compatible transplants.  Complications such as hyperacute rejection, hepatic necrosis and biliary inflammation/stricturing are thought to be related to anti-A and anti-B titers, which is why splenectomy and pheresis are performed for these patients (to decrease production of, and remove antibodies, respectively). 

A mini review can be seen here:

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