Reactivation

Chemotherapy or TNFi for somebody with an isolated hepatitis B core antibody (surface antigen negative)?  Even though chances of reactivation are low, some cases of previously cleared HBV will reactivate during treatment with the above agents.  Prophylaxis with lamivudine is fine if treatment is expected to last less than 1 year; treatment should continue for an additional three months after cessation of (chemotherapy).

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