Monthly Archives: March 2012

Monthly Conference Calendar: April 2012

All lectures and journal clubs will be held in the East campus pathology conference room, from 2:30-3:30, and will follow the weekly hepatopathology conference.  Monday, Apr. 2: Attending Lecture Series: Doug Dieterich, MD, visiting professor from Mount Sinai Hospital, NY … Continue reading

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Clinical Pearl

An inflated Minnesota Tube (the gastric balloon) can be used to tamponade bleeding, rectal varices.

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Chemotherapy or TNFi for somebody with an isolated hepatitis B core antibody (surface antigen negative)?  Even though chances of reactivation are low, some cases of previously cleared HBV will reactivate during treatment with the above agents.  Prophylaxis with lamivudine is … Continue reading

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Definition: HELLP Syndrome

HELLP Syndrome (Hemolytic anemia-haptoglobin,LDH; Elevated LFT- AST and ALT > 40 IU/L; Low Platelets- plt < 150,000) is a serious microangiopathic complication of pre-eclampsia and occurs in the third trimester of pregnancy.

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Lecture: liver disease in pregnancy

This lecture was a nice overview of liver disease in pregnancy.  Fortunately it is not common.  Recall that alkaline phosphatase and alpha fetoprotein (AFP) can be elevated in pregnancy and extend beyond partum.  Most disease occurs in the third trimester. … Continue reading

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The Sunday Chronicles

(Boston, MA) – A hearty congratulations goes to former VP Cheney, after disclosure of his recent transplant.  Get well soon, Dick.

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Pathology: sinusoidal obstruction syndrome

Veno-occlusive disease (VOD) also called sinusoidal obstruction syndrome (SOS) typically occurs within 21 days of an allogenic, hematopoietic stem cell transplant.  These patients may have markedly elevated LFT, and frequently develop ascites because of increased sinusoidal pressures resulting from outflow obstruction.  In this clinical setting, … Continue reading

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