The polycystic liver can be as dramatic in person as it is on film. While most cases are subtle, with multiple, small lobular lesions, some (as in the case shown here) have near obliteration of viable hepatic parenchyma. Whatever is left, however, typically has normal synthetic function.
Polycystic liver disease can be associated with autosomal dominant polycystic kidney disease and cerebral aneurysms, though there is also an autosomal dominant polycystic liver disease (on a different chromasome). If the cyst burden is significant enough, pain may result from mass effect, infection or hemorrhage. Surgical removal is sometimes indicated; a pharmacotherapeutic option includes somatostatin.