Definition: recombinant factor VIIa

Recombinant factor VIIa, despite its risk for thrombosis, can be used in the cirrhotic patient when bleeding is a result of an inadequate coagulation system (ie. massive hematomas, or post-procedural bleeding: dental extractions, liver biopsy, paracentesis).  Its use is likely to be futile in the settings of intraoperative bleeding, portal hypertensive bleeding, severe acidosis or severe deficiency of procoagulant proteins (factors X, V, II and fibrinogen).

Advertisements
This entry was posted in Definition. Bookmark the permalink.

Leave a Reply

Please log in using one of these methods to post your comment:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s