Definition: cavernous transformation

Cavernous transformation describes the perihilar vascular sequelae of a portal vein thrombus, which may develop as soon as 6-20 days after the acute thrombotic event.  The new collateral vessels may be porto-systemic in nature (ie. via left gastric or perisplenic veins) or porto-portal (ie. formation of new intrahepatic branches). 


For an interesting look at the hemodynamics of cavernous transformations, check out the link to this 1995 article in Am J Roentgenol.

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